Publications
Indicators of therapeutic effect in FIT-06, a Phase II trial of a DNA vaccine, GTU(®)-Multi-HIVB, in untreated HIV-1 infected subjects.
Vardas E, Stanescu I, Leinonen M, Ellefsen K, Pantaleo G, Valtavaara M, Ustav M, Reijonen K. Vaccine. 2012 Apr 28.
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Indicators of Therapeutic Vaccine Effect Colour Poster
Immunogenicity and efficacy of Auxo-GTU®-MultiHIV/SIV DNA vaccines in nonhuman primate model of AIDS
Development of The DNA Plasmid Based Genetic Vaccines Vectors, Which Use Segregation Partitioning Function of The Bovine Papillomavirus Type 1
Elicitation of broad CTL response against HIV-1 by the DNA vaccine encoding artificial multi-component fusion protein MultiHIV-Study in domestic pigs
Mölder T, Adojaan M, Kaldma K, Ustav M, Sikut R. Vaccine. 2009 Oct 28.
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Persistent Immune Responses Induced by a Human Immunodeficiency Virus DNA Vaccine Delivered in Association with Electroporation in the Skin of Nonhuman Primates
Martinon F, Kaldma K, Sikut R, Culina S, Romain G, Tuomela M, Adojaan M, Männik A, Toots U, Kivisild T, Morin J, Brochard P, Delache B, Tripiciano A, Ensoli F, Stanescu I, Le Grand R, Ustav M.
Hum Gene Ther. 2009 Oct 5.
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Combining DNA technologies and different modes of immunization for induction of humoral and cellular anti-HIV-1 immune responses
Bråve A, Hallengärd D, Malm M, Blazevic V, Rollman E, Stanescu I, Krohn K.
Vaccine. 2009 Jan 7;27(2):184-6. Epub 2008 Nov 4.
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High prevalence of the CCR5Delta32 HIV-resistance mutation among Estonian HIV type 1-infected individuals
Adojaan M, Mölder T, Männik A, Kivisild T, Villems R, Krispin T, Ustav M.
AIDS Res Hum Retroviruses. 2007 Feb;23(2):193-7.
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GTU-MultiHIV DNA vaccine results in protection in a novel P815 tumor challenge model
Malm M, Sikut R, Krohn K, Blazevic V. Vaccine. 2007 Apr 30;25(17):3293-301.
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Induction of human immunodeficiency virus type-1-specific immunity with a novel gene transport unit (GTU)-MultiHIV DNA vaccine
Blazevic V, Männik A, Malm M, Sikut R, Valtavaara M, Toots U, Ustav M, Krohn K.
AIDS Res Hum Retroviruses. 2006 Jul;22(7):667-77.
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Cross-clade protection induced by human immunodeficiency virus-1 DNA immunogens expressing consensus sequences of multiple genes and epitopes from subtypes A, B, C, and FGH
Malm M, Rollman E, Ustav M, Hinkula J, Krohn K, Wahren B, Blazevic V.
Viral Immunol. 2005;18(4):678-88.
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A DNA HIV-1 vaccine based on a fusion gene expressing non-structural and structural genes of consensus sequence of the A-C subtypes and the ancestor sequence of the F-H subtypes. Preclinical and clinical studies
Krohn K, Stanescu I, Blazevic V, Vesikari T, Ranki A, Ustav M.
Microbes Infect. 2005 Nov;7(14):1405-13. Epub 2005 Oct 4.
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Validation overview of bio-analytical methods
Tuomela M, Stanescu I, Krohn K. Gene Ther. 2005 Oct;12 Suppl 1:S131-8. Review.
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Predominance of a rare type of HIV-1 in Estonia
Adojaan M, Kivisild T, Männik A, Krispin T, Ustina V, Zilmer K, Liebert E, Jaroslavtsev N, Priimägi L, Tefanova V, Schmidt J, Krohn K, Villems R, Salminen M, Ustav M.
J Acquir Immune Defic Syndr. 2005 Aug 15;39(5):598-605.
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Biodistribution and general safety of a naked DNA plasmid, GTU-MultiHIV, in a rat, using a quantitative PCR method
Tuomela M, Malm M, Wallen M, Stanescu I, Krohn K, Peterson P.
Vaccine. 2005 Jan 4;23(7):890-6.
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