Stronger and more
persistent gene expression
The engineered E2 element of the GTU® vector allows for more persistent expression of genes in both non-dividing and dividing cells. It is non-viral, which means that there is neither risk of vector replication nor integration of unwanted DNA into the patient's genome. GTU has been tested in 10 clinical trials to date. It has been found to be safe and well tolerated according to several national regulatory authorities.
Overcoming the inherent weakness
of tissue-specific promoters
Thanks to our engineered E2 element we can overcome the inherent weakness of tissue-specific promoters, enabling better expression of genes where needed. We have vectors available for a range of tissues.
Next-generation vector for gene therapies
Our new gtGTU(R) technology enables the expression of several new types of strong and persistent genes. Expression of, for instance a therapeutic antibody, can be sustained for up to months, challenging current therapeutic modalities.
Antibiotic-free
We are concerned with the growing global problem of antibiotic resistance, and have developed a proprietary technology that allows completely antibiotic-free production of therapeutics.
List of publications
Electroporation as a vaccine delivery system and a natural adjuvant to intradermal
administration of plasmid DNA in macaques.
Todorova B, Adam L, Culina S, Boisgard R, Martinon F, Cosma A, Ustav M, Kortulewski T, Le Grand R, Chapon C.
Electroporation as a vaccine delivery system and a natural adjuvant to intradermal
administration of plasmid DNA in macaques.
Todorova B, Adam L, Culina S, Boisgard R, Martinon F, Cosma A, Ustav M, Kortulewski T, Le Grand R, Chapon C.
Electroporation as a vaccine delivery system and a natural adjuvant to intradermal
administration of plasmid DNA in macaques.
Todorova B, Adam L, Culina S, Boisgard R, Martinon F, Cosma A, Ustav M, Kortulewski T, Le Grand R, Chapon C.
Electroporation as a vaccine delivery system and a natural adjuvant to intradermal
administration of plasmid DNA in macaques.
Todorova B, Adam L, Culina S, Boisgard R, Martinon F, Cosma A, Ustav M, Kortulewski T, Le Grand R, Chapon C.